Research catalog comparison
Melanotan II vs PT-141
Melanotan II and PT-141 are related through melanocortin research, which makes them a common comparison query. They are not identical compounds. This page separates their catalog listings and evidence summaries while showing the current supplier coverage for each.
Live catalog snapshot
In-stock listings only
Melanotan II
- Lowest list price
- $19.49
- 10mg
- Suppliers
- 54
- Active offers
- 63
- Listed quantities
- 8
PT-141
- Lowest list price
- $20.00
- 10mg
- Suppliers
- 53
- Active offers
- 70
- Listed quantities
- 12
Lowest list prices can represent different quantities or forms and are not a direct unit-price comparison. The detailed pages show shipping, coupons, package details, and matching quantity options.
Key differences at a glance
| Comparison | Melanotan II | PT-141 |
|---|---|---|
| Research relationship | A synthetic melanocortin analog studied across several melanocortin pathways. | A related melanocortin peptide studied with a different research emphasis. |
| Price comparison scope | Only compare listings that clearly identify Melanotan II and its quantity. | Only compare listings that clearly identify PT-141 and its quantity. |
| Evidence caution | Related compounds can still have different activity and safety evidence. | Related compounds can still have different activity and safety evidence. |
Research summary starting points
Melanotan II
Melanotan 2 (MT-2) is a synthetic cyclic heptapeptide analogue of alpha-melanocyte-stimulating hormone (α-MSH) with the molecular formula C50H69N15O9 and CAS number 121062-08-6. It functions as a non-selective agonist of melanocortin receptors MC1, MC3, MC4, and MC5, demonstrating up to 1000 times greater potency than endogenous α-MSH. Originally developed for photoprotection through melanogenesis, clinical research has primarily focused on its effects on sexual function, with multiple double-blind placebo-controlled trials demonstrating significant erectogenic properties in men with both psychogenic and organic erectile dysfunction. Additional research areas include metabolic effects, neuroprotection, and appetite suppression. Despite showing clinical efficacy in phase I trials, Melanotan 2 has never received regulatory approval from the FDA, EMA, TGA, or other major health authorities. It remains widely available through unregulated online markets as an unapproved cosmetic tanning agent and sexual enhancement compound, with significant safety concerns including associations with melanoma development, dysplastic nevi, nausea, cardiovascular effects, and unknown long-term risks due to lack of comprehensive safety studies.
Read the sourced Melanotan II overview →PT-141
PT-141 (Bremelanotide) is a synthetic cyclic heptapeptide analogue of alpha-melanocyte-stimulating hormone (α-MSH) developed as a melanocortin receptor agonist. Originally derived from Melanotan II in the 1990s by Palatin Technologies, bremelanotide was specifically developed to address sexual dysfunction after the parent compound unexpectedly caused sexual arousal in clinical trials for tanning. The peptide primarily activates melanocortin receptors MC3R and MC4R in the central nervous system, particularly in the hypothalamic regions involved in sexual response. After extensive clinical development including two large Phase 3 RECONNECT trials involving over 1,200 premenopausal women, bremelanotide received FDA approval in June 2019 for the treatment of acquired, generalized hypoactive sexual desire disorder (HSDD) in premenopausal women. It is marketed as Vyleesi and administered as a 1.75 mg subcutaneous injection at least 45 minutes before anticipated sexual activity. The FDA considers it a first-in-class medication, representing a novel non-hormonal approach to treating sexual dysfunction through central melanocortin pathway activation.
Read the sourced PT-141 overview →Common comparison questions
Are Melanotan II and PT-141 the same compound?
No. Melanotan II and PT-141 are distinct compounds. Compare their identities and evidence separately.
What is the lowest listed Melanotan II price?
The lowest currently indexed in-stock Melanotan II listing starts at $19.49 for 10mg. Compare matching quantities because package size and form affect price.
What is the lowest listed PT-141 price?
The lowest currently indexed in-stock PT-141 listing starts at $20.00 for 10mg. Compare matching quantities because package size and form affect price.
Comparison scope
Peptide Plus compares research-supplier catalog data. This page does not provide medical advice, dosing guidance, or a claim that either compound is appropriate for human use. All listed products are for research purposes only.